Inhibitors stop factor replacement treatment from working. So, hemophilia with inhibitors makes it harder to prevent and stop bleeds.1 Fortunately, several treatment options are available today and research for more is ongoing.1
“As long as you have a positive outlook, you can continue to fight whatever challenges you face.“ — Amalia, Takeda community educator
The treatment you get is based on the amount of inhibitors you have.2 Inhibitor levels can vary from person to person and over the course of time, inhibitor levels can also vary within the same person. These levels are called titer levels.3
Inhibitors are complex. The amount of inhibitors in the blood varies from person to person and within the same person over time.3 If you are diagnosed with inhibitors, your hemophilia care team will consider your inhibitor level, as well as your lifestyle and activities before prescribing one of the following treatment courses:
Since as many as a third of all hemophilia patients may develop inhibitors to their factor treatment, there are screening tests (also called “surveillance” tests) that can help detect inhibitors early on.5 The Bethesda assay is the most widely used method in the United States, while other tests include the activated partial thromboplastin time (APTT) test, specific measurements of clotting factors over time (typically 48 hours), as well as a variant of the Bethesda assay called the Nijmegen-Bethesda assay.5
Consult with your healthcare provider (HCP) and your Hemophilia Treatment Center (HTC) about surveillance testing options that are available to you.5
Be prepared with questions so you can have better conversations with your healthcare provider.
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Hemophilia Treatment Centers (HTCs) provide a range of education and support services.