About hemophilia A

Dive into the details of hemophilia A—what it is, who it affects, when symptoms can occur, and more.

What is hemophilia A?

Hemophilia is a bleeding disorder in which blood does not clot properly. It is usually inherited, and while there is currently no cure for hemophilia, there are treatments that can control and prevent bleeding.1,2

Hemophilia A, also known as classical hemophilia or factor VIII deficiency, is the most common type of hemophilia. It is a genetic disorder resulting in low factor VIII levels.1

Factor VIII (or factor 8) is a clotting factor, which is an essential blood protein needed to stop bleeding.1

70% of hemophilia A is inherited. In about 30% of cases, people with no family history of clotting or coagulation disorders may have a spontaneous gene mutation that causes hemophilia A.3

Doctor treating a patient.

5 fast facts about hemophilia A2,3

About 1 in a million people develop "acquired" hemophilia A4

80 percent icon.

of patients are over the age of 65

Antibodies icon.

Happens when the body produces antibodies that attack factor VIII

Blood drop icon.

Clinical presentation varies from life-threatening bleeds on one end to mild or no bleeds on the other end

Keep exploring

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What are the symptoms of hemophilia A?

Doctor discussing treatment options with a patient during an appointment.

Treatment options for hemophilia A

Pharmacist organizing the medicines in the drawer.

How is hemophilia A diagnosed?

  1. Centers for Disease Control and Prevention. What is hemophilia? https://www.cdc.gov/ncbddd/hemophilia/facts.html. Accessed February 12, 2023.
  2. National Organization for Rare Disorders. Hemophilia A. https://rarediseases.org/rare-diseases/hemophilia-a/. Accessed February 12, 2023.
  3. Srivastava A, Santagostino E, Dougall A, et al. WFH Guidelines for the Management of Hemophilia, 3rd edition. Haemophilia. 2020:26(suppl 6):1-158. https://doi.org/10.1111/hae.14046
  4. Haider MZ, Anwer F. Acquired Hemophilia. In: StatPearls. Treasure Island (FL): StatPearls Publishing; September 26, 2022.